Toxic shock syndrome (TSS)
May 7, 2026
Toxic shock syndrome (TSS) is a form of blood poisoning. It rarely occurs, but it can be fatal.
Signs & Symptoms
Symptoms come on fast and are often severe, such as:
- High sudden fever; sore throat.
- Flat, red, sunburn-like rash on the trunk of the body that spreads. The skin on the palms of the hands and soles of the feet peels. Redness of the lips, eyes and tongue may also occur.
- Muscle aches, extreme fatigue and weakness.
- Abdominal pain, diarrhea, vomiting.
- Low blood pressure. Rapid pulse.
- Dizziness, confusion, fainting.
Causes
Toxic shock syndrome is caused when certain bacteria release toxins in the blood. It can result from wounds or an infection in the throat, lungs, skin or bone. Until recently, it affected mostly women who used super absorbent tampons. These trapped and allowed bacteria to grow and spread. Now, TSS is more often due to post-surgery complications and other wound infections including a C-section surgery.
Treatment
Toxic shock syndrome requires emergency medical care.
- Vomiting, then abdominal pain, and profuse, watery diarrhea.
- Muscle aches, headaches, sore throat, and “pinkeye” with a discharge that is clear.
- High fever without a skin rash, but with any other symptom listed in this question.
Self-Care / Prevention
- Practice good hygiene. Wash your hands often.
- Keep wounds clean. See your doctor for signs of an infection (increased redness, swelling and/or pain, pus and/or fever).
- Don’t use tampons if you’ve had TSS in the past.
- Change tampons and sanitary pads every 4 to 6 hours or more often. When you can, use sanitary napkins instead of tampons. Alternate tampons with sanitary pads or mini-pads during a menstrual period. Lubricate the tampon applicator with a water-soluble (nongreasy) lubricant, like K-Y Jelly®, before insertion.
Triage Questions
Question 1
Are signs and symptoms of toxic shock syndrome listed on this page present?